Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Frailty
研究概览
简要总结
After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS). Other complications have been described, including ICU-acquired weakness, leading to increased morbidity and mortality after discharge. Actually, risk factors associated with post-ICU fatigue self-reported are not really known.
详细描述
Frailty, defined as a decrease in physiological reserves leading to an alteration in the mechanisms of adaptation to stress, increases the incidence of PICS and could therefore be a cause of post-ICU fatigue self-reported.
The aim of this study is to identify a relationship between markers of frailty, ICU-AW, ICU story and the post-ICU fatigue self-reported 6 months discharge in patients with prolonged ICU stays.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a length of stay in intensive care > or equal to 7 days, or mechanical ventilation > or equal to 5 days
排除标准
- •Scheduled surgery with admission in ICU
- •Pregnancy
- •Guardianship
结局指标
主要结局
Frailty
时间窗: 1 year
Relationship between frailty markers (CFS, IADL, sarcopenia and myosteatosis), ICU-AW, ICU story and post-ICU fatigue self-reported
次要结局
- ICU-acquired weakness and fatigue(1 year)
- Kinetic of muscle mass loss and post-ICU fatigue self-reported(1 year)
- Fatigue, quality of life, anxiety and depressive disorder(1 year)
- Fatigue(1 year)