TSDIST study: Taste and smell disturbances in graft versus host disease patients

Completed

• Conditions: smell changes; smaak-en reukstoornissen; taste changes; 10024324

• Registration Number: NL-OMON48338
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

adult allogeneic hematopoietic stem cell transplantation recipients with graft versus host disease

Exclusion Criteria

allogeneic HSCT recipients without GVHD, patients with neurodegenerative diseases and smokers

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Qualitative and quantitative measurements of taste disturbances -<br /><br>Quantitative measurements of smell disturbances</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Amount of (un)stimulated salivary flow - (Oral health related) quality of<br /><br>life - Score overall GvHD - Oral GvHD (subjective/objective) - Perception of<br /><br>taste and smell changes</p><br>