TASTE II Trial - Impact of taste and smell training and structured, individualized nutritional intervention to improve taste perception in patients receiving chemotherapy - a multicenter trial

Not Applicable

Suspended

• Conditions: R43.2; Parageusia

• Registration Number: DRKS00020361
• Lead Sponsor: Hubertus Wald Tumorzentrum - Universitäres Cancer Center HamburgUniversitäres Klinikum Hamburg- Eppendorf (UKE)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with an objective taste disorder (measured using taste strips Taste Strips) with a point score <9 points
- Patients with active cancer receiving outpatient chemotherapy including taxanes, platinum derivatives, athracyclines and / or antimetabolites
- Age <18 years
- existing written declaration of consent

Exclusion Criteria

- Presence of a genetic metabolic disorder
- Treatment / previous treatment for an eating disorder (anorexia, bulimia, binge eating)
- Parenteral nutrition, enteral supplementary food (food via PEG or PEJ) or with high-calorie drinking food (if> 50% of the energy requirement is covered by drinking food) under therapy for tumor cachexia
- Radiation in the head and neck area
- pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is the improvement of the objective taste perception by 2 Taste strip points at week 12 in at least 50% of the patients from the intervention group compared to the control group.