Central Hypothyroidism and Adjusted Thyroxine dose Study (CHATS): impact of increasing free thyroxine levels in patients with hypopituitarism - CHATS
- Conditions
- Central (secondary/tertiary) hypothyroidism (subclinical)
- Registration Number
- EUCTR2004-005184-15-GB
- Lead Sponsor
- Christie Hospital NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients aged 20-70 with hypopituitarism and free thyroxine levels within the lower third of the reference range
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
thyrotoxicosis, uncontrolled cardiac arrhythmias or unstable ischaemic heart disease, treatment with amiodarone/lithium within the last 6 months, acromegaly, Cushing's disease
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method