Cognitive-motor Exercise for Stroke Patients in Function, Cognition and Related Brain Changes.

Not Applicable

Recruiting

• Conditions: Stroke

• Registration Number: NCT06362512
• Lead Sponsor: The Hong Kong Polytechnic University

Brief Summary

The purpose of this study is to evaluate a cognitive-motor exercise on dual-task interference during dual-task ankle movement and the corresponding alterations of brain activity.

Detailed Description

The prevalence rate of stroke increased by 106.0% (93.7-118.8) from 1990 to 2019 in China, and stroke burden is still severe. Community ambulation is an important factor that influences health-related quality of life after a stroke.In daily living, effective community ambulation requires the ability to maintain balance and walking function while engaging in other tasks that demand attentional resources simultaneously (i.e., dual-tasking). Increasing evidence has shown that stroke patients have more problems with dual-task balance and walking function than their age-matched able-bodied peers. stroke individuals were found to have more reduction in both the walking speed and cognitive recall than control group during walking with remembering a shopping list. Hence, since stroke victims must reintegrate into community, this kind of cognitive-motor interference needs to be thoroughly studied.

Study Timeline

• Status Verified: 2024-04
• Study First Submitted: 2024-04-08
• Study First Submitted QC: 2024-04-08
• Study First Posted: 2024-04-12
• Study Start: 2024-06-17
• Last Update Submitted: 2024-07-02
• Last Update Posted: 2024-07-05
• Primary Completion: 2026-04
• Study Completion: 2026-04

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Dual-task step frequency	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	step frequency under dual-task condition will be recorded
Dual-task cognitive performance accuracy	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	Number of correct responses will be measured during dual-task conditions

Secondary Outcome Measures

Name	Time	Method
Blood oxygenation level changes of the brain	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	Blood oxygenation level changes will be measured using Magnetic Resonance Imaging during dual-task conditions
Dual-task No.steps	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	No.steps under dual-task condition will be recorded
Dual-task amplitude of ankle movement	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	Amplitude of ankle movement under dual-task condition will be recorded
Dual-task correct reaction time	before the initiation of training,after 6 weeks of training, 6 weeks after termination of the training	Correct reaction time under dual-task condition will be recorded

Trial Locations

Locations (1)

The Hong Kong Polytechnic University; 🇨🇳 Hong Kong, China