Comparing the efficacy of enteral and parenteral zinc supplementation in childre
Phase 3
Recruiting
- Conditions
- zinc deficiency.Dietary zinc deficiency
- Registration Number
- IRCT20190522043672N4
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
Age between 1 month and 10 years
Admission to intensive care units of Akbar Hospital
Predicted length of stay in the pediatric intensive care unit of more than 4 days
Exclusion Criteria
Lack of parental consent
Renal failure
Multi-organ damage
Known zinc deficiency (eg enteropathy acrodermatitis)
Pre-existing or newly diagnosed bone marrow failure or diabetes mellitus
In-place care or anticipated survival restriction orders.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method C-Reactive Protein (CRP). Timepoint: The first day before the start of the intervention and seven days after the start of the intervention. Method of measurement: (ELISA) Enzyme-linked immunosorbent.;Plasma copper to zinc ratio. Timepoint: The first day before the start of the intervention and seven days after the start of the intervention. Method of measurement: Plasma mass spectrometry.;Complete blood count. Timepoint: The first day before the start of the intervention and seven days after the start of the intervention. Method of measurement: complete blood cell count test device.
- Secondary Outcome Measures
Name Time Method Duration of hospitalization. Timepoint: The seventh day after the start of the intervention. Method of measurement: Completing the checklist.;Duration of ventilator use (days). Timepoint: The seventh day after the start of the intervention. Method of measurement: Completing the checklist.;Mortality percentage. Timepoint: The seventh day after the start of the intervention. Method of measurement: Completing the checklist.