sefulness of cardiac computed tomography in aortic stenosis patients

Not Applicable

Recruiting

• Conditions: Aortic stenosis

• Registration Number: JPRN-UMIN000025047
• Lead Sponsor: Ehime University Graduate School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-12-01
• Last Update Posted: 17 October 2023
• Study Completion: 2026-12-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Not provided

Exclusion Criteria

1.Clinically unstable patients (Acute myocardial infarction, unstable angina, and malignant arrhythmia) 2.Patients with a history of hypersensitivity to iodine or iodinated contrast media 3.Patients who are pregnant or breastfeeding 4.When the research director or the research subinvestigator determines that it is not appropriate to participate in the research

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the feasibility of left ventricular CT MP-strain, LIE-CT, CT-ECV for predicting outcome: all-cause mortality, cardiac death, hospitalization due to heart failure, therapeutic effect (aortic valve replacement, transcatheter aortic valve implantation, transcatheter aortic valve replacement )

Secondary Outcome Measures

Name	Time	Method
1) To evaluate CT MP-strain value compared with strain value derived from cardiac MRI or US. 2) To compare CT MP-strain with cardiac anatomical, functional or myocardial characteristic information measured by cardiac MRI or US (left ventricular ejection fraction, wall thickness, myocardial volume, late gadolinium enhancement, T1 mapping, T2 mapping, phase contrast) 3) To evaluate other parameters from CT strain analysis (Strain rate, minimum principal strain etc.) 4) To evaluate LIE-CT/CT-ECV derived from cardiac CT compared with LGE-MRI/ECV derived from cardiac MRI.