Effect of combined dietary supplementation and resistance exercise on the muscle mass, muscle strength, and physical performance in transfusion-dependent thalassemia adults with sarcopenia

Phase 1

• Conditions: Transfusion dependent thalassemiasSarcopeniaOsteopenia and osteoporosis; Transfusion dependent thalassemias; Sarcopenia; Osteopenia and osteoporosis; Dietary supplementation; Resistance exercise; Resistact

• Registration Number: TCTR20220531003
• Lead Sponsor: The Thai Red Cross society

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-31
• Study Completion: 2022-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

Diagnosed transfusion dependent thalassemia
Diagnosed sarcopenia according to criteria of Asian working group on sarcopenia 2019
Age >= 18 years
New York Heart Association (NYHA) functional class I

Exclusion Criteria

not willing to or unable to complete the project for the full 6 month period
pregnancy
co-morbidites with heart , lung , liver , kidney disease which is not suitable to receive dietary supplementation and resistance exercise program

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
muscle mass 6 months BMD ,muscle strength 6 months hand grip strength ,physical functions 6 months 6-meter walk test

Secondary Outcome Measures

Name	Time	Method
Quality of life 6 months SarQol score