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Comparative analysis of oral and intestinal environment in healthy subject and patients with oral disease.

Not Applicable
Conditions
Men and women
Registration Number
JPRN-UMIN000031334
Lead Sponsor
Hiyoshi Oral Health Clinics
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
150
Inclusion Criteria

Not provided

Exclusion Criteria

(A-1) Subjects who have denture or implants. (A-2) Smoker (A-3) Subjects who consumed antibiotics during last 6 months. (A-4) Subjects who did mouth cleaning, eating, or drinking except water during last 1 hour. (A-5) Subjects who did mouth cleaning from last night to sampling. (A-6) Subjects who is pregnant. (A-7) Subjects who have been determined ineligible by principal investigator. (B-1) Subjects who have denture or implants. (B-2) Smoker (B-3) Subjects who consumed antibiotics during last 6 months. (B-4) Subjects who is in orthodontic treatment. (B-5) Subjects who did mouth cleaning, eating, or drinking except water during last 1 hour. (B-6) Subjects who is pregnant. (B-7) Subjects who have been determined ineligible by principal investigator. (C-1) Subjects who have denture or implants. (C-2) Smoker (C-3) Subjects who consumed antibiotics during last 6 months. (C-4) Subjects who is in orthodontic treatment. (C-5) Subjects who did mouth cleaning, eating, or drinking except water during last 1 hour. (C-6) Subjects who is pregnant. (C-7) Subjects who have been determined ineligible by principal investigator. (D-1) Subjects who have denture or implants. (D-2) Smoker (D-3) Subjects who consumed antibiotics during last 6 months. (D-4) Subjects who is in orthodontic treatment. (D-5) Subjects who did mouth cleaning, eating, or drinking except water during last 1 hour. (D-6) Subjects who is pregnant. (D-7) Subjects who have been determined ineligible by principal investigator. (E-1) Subjects who did mouth cleaning, eating, or drinking except water during last 1 hour. (E-2) Subjects who have been determined ineligible by principal investigator.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
16S rRNA gene-based metagenome analysis and metabolome analysis of oral cavity samples
Secondary Outcome Measures
NameTimeMethod
* 16S rRNA gene-based metagenome analysis and metabolome analysis of fecal samples * Background research * Questionnaire
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