Analysis of Predictive Factors for Urinary Leakage After Partial Nephrectomy for Renal Hilum Tumors

Active, not recruiting

• Conditions: Partial Nephrectomy; Renal Hilum Tumors; Urinary Leakage

• Registration Number: NCT06916910
• Lead Sponsor: First Affiliated Hospital of Fujian Medical University

Brief Summary

In this study, we plan to explore the risk factors closely related to the occurrence of urinary leakage after partial nephrectomy for renal hilum tumors through retrospective analysis of multicenter clinical data, thereby providing clinical guidance value for the prevention of postoperative urinary leakage.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-09-18
• Study First Submitted: 2025-02-24
• Status Verified: 2025-04
• Study First Submitted QC: 2025-04-01
• Last Update Submitted: 2025-04-01
• Study First Posted: 2025-04-08
• Last Update Posted: 2025-04-08
• Primary Completion: 2025-09-18
• Study Completion: 2025-09-18

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• CT or MRI angiography indicates a renal hilum tumor, and the patient has undergone partial nephrectomy;
• The Eastern Cooperative Oncology Group (ECOG) performance status score is between 0 and 1, and the age is between 18 and 75 years old;
• The clinicopathological data are complete;
• There is no infection, autoimmune disease, hematological disease, or other malignancies.

Exclusion Criteria

• The patient has surgical contraindications;
• There are congenital malformations of the urinary system, obstructive nephropathy, or other diseases that seriously affect the function of the urinary system before surgery;
• The patient has received relevant treatments that may affect the results of this study, such as radiotherapy in the kidney area, a history of kidney surgery, etc.;
• There are tumors in both kidneys.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative urinary leakage	the postoperative perirenal drainage volume being greater than 50 ml for 7 consecutive days and the creatinine level of the drainage fluid being similar to that of urine(μmol/L), or postoperative urinary leakage being suspected by imaging examination.	Postoperative urinary leakage is defined as the postoperative perirenal drainage volume being greater than 50 ml for 7 consecutive days and the creatinine level of the drainage fluid being similar to that of urine(μmol/L), or postoperative urinary leakage being suspected by imaging examination.

Trial Locations

Locations (1)

first hospital affiliated of Fujian medical university; 🇨🇳 Fuzhou, Fujian, China