The effect of rumenic acid rich conjugated linoleic acid supplementation on cognitive functioning

Withdrawn

Conditions: cognitieve stoornis
cognitive decline
impaired brain functioning
10007951

Registration Number: NL-OMON48753

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 52

Inclusion Criteria

- Aged 65 years or older
- At risk of cognitive impairment/ memory complaints
- Able to understand and perform the study procedures

Exclusion Criteria

- Body Mass Index (BMI) >35 kg/m2
- Current use of medication belonging to the *sartans* or *glitazones*
- Current use of >500 mg/day of acetylsalicylic acid
- Current use of medication that affects inflammation (anti-inflammatory
medication)
- Fish consumption of more than 1 serving per week
- Current or recent (<1 month) use of fish oil supplements
- Current or recent (<1 month) use of anti-inflammatory dietary supplements
such as quercetin, curcumin, resveratrol, and/or other flavonoids
- Diabetes mellitus
- Having a disease which interferes with the effect of the RAR-CLA supplement
and/or with the outcome measure (cognitive functioning) as judged by medical
doctor
- Swallowing problems
- Current participation in other scientific research with the exception of
EetMeetWeet!

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter is the performance on episodic memory.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary parameters entail working memory, attention, executive functioning,<br /><br>and psychomotor speed as measured with a battery of cognitive tests, the<br /><br>evaluation of rumenic acid supplementation on anxiety, depressive symptoms,<br /><br>quality of life (measured with questionnaires), and fatty acid status (measured<br /><br>in blood). </p><br>