Comparison of HACOR and ROX score to predict failure of Non-invasive respiratory assist devices like NIV, HFNC
- Conditions
- Health Condition 1: J960- Acute respiratory failure
- Registration Number
- CTRI/2022/11/047053
- Lead Sponsor
- Bharati Hospital and Research centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
All Patients who are 18 years of age or older will be screened for AHRF, defined as tachypnea (respiratory rate > 25/ min), PaO2/FiO2 ratio <300, PaCO2 <45mmHg in absence of history of Chronic Respiratory Failure. All these patients will be receiving COT.
Patients with AHRF who fail COT will be identified by any of the following criteria-
1.Worsening tachypnea (RR > 35) ,
2.Oxygen saturation < 88% on FiO2 0.6 on Venturi mask
3.Signs of respiratory distress( decreased consciousness, tachycardia, paradoxical respiratory movements, use of accessory muscles)
1)Chronic respiratory failure,
2)Hemodynamic instability (systolic BP < 90 mm Hg or MAP < 65mm Hg despite use of vasopressors, ( Noradrenaline requirement > 0.1 mcg/kg/min or Dopamine requirement > 10mcg/kg/min )
3)A do-not-intubate order
4)Anticipated life expectancy less than 90 days
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Predicting failure of non invasive respiratory therapy (Both HFNC and NIV) in acute hypoxemic respiratory failure by calculating ROX index and HACOR scoreTimepoint: At 1 hour and 6 hours of initiation of NIV or HFNC
- Secondary Outcome Measures
Name Time Method To compare effectiveness of ROX index and HACOR score for predicting failure of non invasive respiratory therapy (NIV and HFNC) as defined by need of intubationTimepoint: 18 months;To study predictors of failure of non invasive respiratory therapyTimepoint: 18 months