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Effect of Inhaled Colistin on the Treatment of Pulmonary Infections Caused by Ventilator with Multi-drug Resistant Acinetobacter at in Intensive Care Unit of Rasoul-Akram Hospital in 2016-17

Phase 2
Conditions
Pulmonary infection Caused by Ventilator.
Pulmonary mycobacterial infection
Registration Number
IRCT2017091236068N1
Lead Sponsor
Vice chancellor for Research and Technology of Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
114
Inclusion Criteria

age ranging: over 16 years; multi-drug resistant patients especially multidrug-resistant Acinetobacter; without sensitivity to polymyxins; positive culture (Colony count: BAL 104 or Mini BAL 105). Exclusion criteria: patient death; incidence of sensitivity to polymyxins; reduced GFR <0.25; incidence of bronchospasm evidences in treatment group.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The severity of pulmonary infection using CPIS. Timepoint: At the first, third and seventh days after intervention. Method of measurement: Using Clinical Pulmonary Infection Score (CPIS) Calculator; CPIS more than 6 at baseline or at 72 h: pneumonia; CPIS less or equal to 6 at 72 hours patient: without pneumonia.
Secondary Outcome Measures
NameTimeMethod
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