Comparing the effect of two different concentrations of the drug ropivacaine which causes numbness locally on application in the throat passage in patients undergoing thyroid surgery under general anaesthesia.
- Conditions
- Health Condition 1: E00-E07- Disorders of thyroid gland
- Registration Number
- CTRI/2019/04/018426
- Lead Sponsor
- Government Medical College and Hospital Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
American Society of Anaesthesiologists (ASA) physical status I /II.
Patients undergoing thyroid elective surgery under GA.
1.Morbid obesity (BMI > 35 kg.m-2).
2.Patients with severe cardiovascular, liver, and kidney diseases.
3.Patients with allergies to amide local anaesthetics.
4.Patients with increased risk of regurgitation and aspiration of gastric content.
5.Patients with difficult airway or history of maxillofacial and neck surgery.
6.Patients with history of chronic respiratory disease such as Chronic ObstructivePulmonary disease, chronic coughing or asthma, recent respiratory tract infection or smoking.
7.Pregnancy.
The elimination criteria will be as follows: reoperation because of serious adverse events such as bleeding, anaesthesia time more than 3 h, and delayed extubation (more than 1 h without extubation) or transfer to the ICU with the tube.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the haemodynamic responses during intubation and extubation as well as post operative incision pain and sore throat. <br/ ><br>Timepoint: Immediately after extubation. <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare the haemodynamic responses during intubation and extubation as well as post operative incision pain and sore throat. <br/ ><br>Timepoint: T0-Baseline, T1-before intubation, T2-immediately after intubation, T3-5 mins after intubation, T4-at the end of surgery, T5-immediately after extubation and T6- 5 mins after extubation. <br/ ><br>Patients will also be followed up to 6 hours after surgery to record the degree of sore throat and incision pain assessed by visual analogue scale (VAS) <br/ ><br>