A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients
- Conditions
- Focus on Laser Treatment of Nevus of Ota in Thai Patients
- Interventions
- Other: Laser (QS, Picosecond laser)
- Registration Number
- NCT04481178
- Lead Sponsor
- Mahidol University
- Brief Summary
A retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients
- Detailed Description
Nevus of Ota is a benign dermal melanocytic nevus found most commonly in Asians. About 50-60% of all cases have the age of onset at birth or within the first year of life, others appear before puberty. It typically presents as a unilateral mottled blue-gray macules and patches distributed along the first and second branches of trigeminal nerve. Due to its marked hyperpigmentation on the face which does not resolved spontaneously, patients may experience psychosocial disturbances and often seek for treatments. Based on selective photothermolysis theory, Q-switched lasers (ruby 694nm, alexandrite 755nm, Nd:YAG 1064nm) have been used for the treatment of nevus of Ota with a success rate of 95% after 6-8 sessions. Reported complications from the lasers are hypopigmentation(15.3%), hyperpigmentation(2.9%), texture changes (2.9%), and scarring (1.9%). Siriraj Skin Laser Center provides laser treatment for nevus of Ota using mainly Q-switched Nd:YAG laser and Picosecond laser. The study of efficacy and complications of Q-switched Nd:YAG and Picosecond laser in the treatment of Nevus of Ota in Thai patients has never been reported. Therefore, we conduct a retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 79
- Patient with Nevus of Ota
- Complete data between January 2008 - December 2018
- Incomplete data
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description patients with nevus of Ota Laser (QS, Picosecond laser) patients with nevus of Ota who had been treated with laser at Siriraj hospital
- Primary Outcome Measures
Name Time Method Efficacy of laser treatment in paitients with Nevus of Ota 2008-2018 Fading of lesions after treatment by chart review
- Secondary Outcome Measures
Name Time Method Complication of laser such as hyperpigmentation, hypopigmentation, and scars 2008-2018 Complication of laser such as hyperpigmentation, hypopigmentation, and scars
Relapse rate after laser treatment 2008-2018 rate of recurrence after treatment
Trial Locations
- Locations (1)
Faculty of Medicine Siriraj Hospital
🇹ðŸ‡Bangkoknoi, Bangkok, Thailand