The Enhanced Dementia Diagnosis (EDD study) study-Evaluating new diagnostics for Alzheimer's Disease against usual care for people attending memory clinics within Australia.

Not Applicable

• Conditions: Dementia; Neurological - Dementias

• Registration Number: ACTRN12624001059550
• Lead Sponsor: The Florey Institute of Neuroscience and Mental Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-09-02
• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

1) Memory clinic physicians, (2) Memory clinic patients being considered for a diagnosis of Mild Cognitive Impairment or Alzheimer’s disease dementia, and (3) Patients’ care partners.

1) Memory clinic physicians
Specialists (or trainee specialists) who diagnose dementia as part of their usual clinical practice’, private or public.

2) Memory clinic patients
1. Age is greater than or equal to 40 years.
2. Attending a memory clinic seeking assessment for cognitive concerns or dementia.
3. Individuals assessed with dementia have an identified care partner (e.g., family member, spouse, caregiver).

3)Memory clinic patients care partner
An individual, aged over 18, who is nominated as a care partner by the patient.

Exclusion Criteria

1) Memory clinic physicians
Not practicing in an EDD program participating memory clinic.

2) Memory clinic patients
1. Memory clinic physician assesses the patient as unsuitable for dementia diagnostic workup, based on:
a. No evidence of cognitive or behavioural impairment.
b. Potential patient has severe dementia or other illness such that the person will receive no benefit from undergoing further investigation in the opinion of the memory clinic physician.
2. Patient and/or ‘care partner’ is unable or unwilling to provide informed consent for the study.
3. Amyloid pathology status obtained by PET/CSF/Blood are already known to the memory clinic physician.
4. The patient is unable to undergo Aß-PET and FDG-PET.
5. Individuals with advanced care directive that is in potential conflict with consent, for e.g., I don’t want to be involved in research studies”.

Study & Design

• Study Type: Interventional
• Study Design: Not specified