The effect of plasma therapy in the treatment of patients with COVID-19
Phase 3
- Conditions
- COVID-19 infection.Pneumonia due to SARS-associated coronavirusJ12.81
- Registration Number
- IRCT20210714051887N1
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
Willingness to participate in the studyPeople over the age of 18People with severe form of COVID-19 disease (shortness of breath, respiratory frequency = 30 / min,, blood oxygen saturation = 93%,, partial pressure of arterial oxygen to fraction of inspired oxygen ratio <300,, percentage of pulmonary involvement more than 50 in 24-48 hours,)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Body temperature. Timepoint: On days two, three and 7 after hospitalization and receiving plasma. Method of measurement: Thermometer device.;Blood Saturated Oxygen Levels. Timepoint: On days two, three and 7 after hospitalization and receiving plasma. Method of measurement: Pulse oximeter.;C-reactive protein (CRP) Factor. Timepoint: On days two, three and 7 after hospitalization and receiving plasma. Method of measurement: Blood Test.
- Secondary Outcome Measures
Name Time Method Duration of hospitalization of the patient. Timepoint: End of hospitalization or death of the patient. Method of measurement: By day.;Heart rate. Timepoint: On days two, three and 7 after hospitalization and receiving plasma (patient receives plasma treatment on the second day of hospitalization. Method of measurement: Monitoring device.;Lung lesions on CT scan. Timepoint: On days two, three and 7 after hospitalization and receiving plasma (patient receives plasma treatment on the second day of hospitalization). Method of measurement: Lung lesions with lung CT scan.;D-dimer Factor. Timepoint: On days two, three and 7 after hospitalization and receiving plasma (patient receives plasma treatment on the second day of hospitalization. Method of measurement: blood test.