Comparative study of the effect of Dexmedetomidine-Lignocaine based Opioid free anaesthesia versus Standard General Anaesthesia on inflammatory markers in patients undergoing TAH
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/02/063028
- Lead Sponsor
- Maulana Azad Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA GRADE 1-2
Exclusion Criteria
Any cardiac, renal or hepatic diseases
Patients having acute infections or hepatic illnesses.
BMI > 30 kg/square metres.
History of allergies to therapeutic drugs used in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change of plasma cytokine levels of IL6 and TNF alpha from baseline to immediately after the end of surgery and 24 hours after the end of surgery.Timepoint: Baseline to immediately after the surgery and 24 hours after the end of surgery.
- Secondary Outcome Measures
Name Time Method The change in inflammatory bio markers : Procalcitonin, C-reactive protein, D-dimer, from baseline to immediately after the surgery & 24 hours after the end of surgery.Timepoint: Duration of post operative analgesia.