Attentional Bias Retraining in Veterans
- Conditions
- Posttraumatic Stress Disorder
- Registration Number
- NCT02041572
- Lead Sponsor
- VA Pacific Islands Health Care System
- Brief Summary
The study has two goals. First to develop a computer-based intervention meant to alter cognitive biases that contribute to ongoing PTSD symptoms. Second, we sought to pilot test the intervention in a small sample of veterans for feasibility and acceptability.
- Detailed Description
Aim 1: Develop Attentional Bias Retraining protocol (Phase 1)
* 1.1 Computerized assessment \& retraining programs
* 1.2 Procedures and measures
Aim 2: Implement in pilot sample (Phase 2)
* 2.1: Assess feasibility and tolerability
* 2.2: Collect pilot data to plan future studies
* 2.3: Efficacy estimates based on changes in response time to dot probe task
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 22
- Participated in ground combat operations in Vietnam
- Scored 40 - 80 on PTSD Checklist - Military version
- Availability and willingness to attend 2x weekly computer sessions for 6 weeks
- Active substance dependence
- Significant cognitive impairment
- Current and active suicidal or homicidal ideation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Post-traumatic Checklist - Military version (PCL-M) Change from Baseline and Post-treatment (1 month after last training session) PCL-M assess the 17-cardinal symptoms of PTSD.
- Secondary Outcome Measures
Name Time Method Attentional bias scores Change from Baseline and Post-treatment (1 month after last training session) Attentional bias scores represent participants cognitive bias to orient towards trauma-relevant information more quickly than neutral information.
Trial Locations
- Locations (1)
National Center for PTSD
🇺🇸Honolulu, Hawaii, United States
National Center for PTSD🇺🇸Honolulu, Hawaii, United States