The effect of vitamin D supplementation on blood pressure in hypertensive patients with vitamin D deficiency
- Conditions
- Essential (primary) hypertensionhypertension.
- Registration Number
- IRCT2012090310724N1
- Lead Sponsor
- Vice chancellor for research, Shahid Sadoogi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 48
patients with Systolic Blood Pressure equal or more than 140 mmHg ; and Diastolic Blood Pressure equal or more than 90 mmHg. ; and serum 25-hydroxy vitamin D3 lower than 30 ng/ml ; living in Yazd province; aged 25-50 years; not to be alcohol user or smoker or addicted ; without any liver or Coronary-artery or renal or Gastro Intestinal disorders; not using oral or injection of corticosteroids; not using cardiac glycosides or antiepileptic drugs; not using multi vitamins or supplements containing vitamin D, Calcium, Magnesium, Phosphorus or their analogs in past 3 mounts; not using injection of vitamin D in past 6 mounts; Exclusion criteria: any change in dosage or type of anti hypertension drugs; not following the study protocol.
Exclusion criteria: any change in dosage or type of anti hypertension drugs; not following the study protocol.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hypertension. Timepoint: before and 8 week after intervention. Method of measurement: mercurial sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Serum Calcium. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements.;Serum 25- Hydroxy vitamin D. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements _nmol/lit.;Serum PTH. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements.;Serum phosphorus. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements.