To assess the effect of intravenous paracetamol on reduction of hourly average consumption of epidural levobupivacaine and fentanyl mixture in labouring parturients
Phase 4
- Conditions
- Health Condition 1: null- Pregnant Parturient
- Registration Number
- CTRI/2013/09/003968
- Lead Sponsor
- Department of anaesthesia and intensive care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
•American Society of Anesthesiologists (ASA) grade I and II
•Age >18 years
•Primigravida
•Single gestation
•Cephalic presentation at >= 36 wk of gestation
•In early spontaneous labour (cervical dilation <= 5 cm)
•Baseline pain score > 30 (on a 0-100 VAS)
•Able to use PCEA pump
•Requesting epidural analgesia for labour
Exclusion Criteria
•Refusal by parturient
•Parturients who had received parenteral opioids in the last 4 hours
•Systemic and local sepsis
•Deranged coagulation profile
•Parturients having multiple pregnancies and premature labour
•Obstetric complications (e.g., premature rupture of amniotic membranes)
•Noncephalic presentations
•Allergy to study drugs, i.e., paracetamol, levobupivacaine and fentanyl
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method