Preoperative oral paracetamol versus intraoperative intravenous paracetamol: plasma levels in the recovery room

Phase 4

Completed

• Conditions: Postoperative plasma paracetamol levels; Postoperative pain scores; Postoperative analgesia requirements; Length of stay in recovery; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12609000908235
• Lead Sponsor: Christchurch Public Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-10-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Day case arthroscopies
Suitable for laryngeal mask anaesthesia
American Society of Anaesthesiologists (ASA) 1 & 2
Body mass index (BMI) less than 35

Exclusion Criteria

Contraindication to paracetamol
BMI over 35
Requiring intubation rather than laryngeal mask airway (LMA) use
Requiring any other intraoperative analgesics other than IV fentanyl

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma paracetamol levels from venous blood sample taken from contralateral arm to the drip.<br>Assay performed by Canterbury Health Laboratories using a colourimetric assay on the c8000 analysers. Units in mcmol/l.[30 minutes after arrival in the recovery room]

Secondary Outcome Measures

Name	Time	Method
Postoperative pain scores at 10 minute intervals using a 100mm visual analogue scale (VAS)[10 minute intervals until discharge from recovery];Postoperative rescue analgesia requirements (fentanyl mcg)[Total amount required during the patient's stay in recovery];Duration of stay in recovery ie how long it took for patient to reach standard discharge criteria from recovery[Duration of stay in reocvery]