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To compare the effect of bous intravenous dose of Dexmedetomidine versus Magnesium Sulphate on induction dose of Propofol in patients undergoing general anaesthesia

Not Applicable
Conditions
Health Condition 1: K35-K38- Diseases of appendixHealth Condition 2: K20-K31- Diseases of esophagus, stomach and duodenumHealth Condition 3: K00-K14- Diseases of oral cavity and salivary glandsHealth Condition 4: H60-H95- Diseases of the ear and mastoid processHealth Condition 5: N60-N65- Disorders of breastHealth Condition 6: K80-K87- Disorders of gallbladder, biliary tract and pancreasHealth Condition 7: K40-K46- Hernia
Registration Number
CTRI/2023/08/056866
Lead Sponsor
DR ANAND S
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

a. ASA Grade I and Grade II patients

b. Age 18 yrs –60yrs.

c. Elective surgeries

Exclusion Criteria

a. Refusal of consent

b. Known or anticipated

difficult airway.

c. Emergency surgeries.

d. Pregnant patients.

e. Patients with heart

block

f. Patients on Beta

blockers

g. Bradycardia

h. BMI >30kg/m2

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
For comparing the dose of Propofol needed during induction of anaesthesia after giving a bolus dose of Dexmedetomidine or Magnesium Sulphate or Normal saline in general anaesthesiaTimepoint: Baseline,After Drug bolus,After propofol induction
Secondary Outcome Measures
NameTimeMethod
a) To check the intubation response between the three groups-heart rate,blood pressure,saturation. <br/ ><br>b) Time required for TOF value to change from 0 to 1 <br/ ><br>Timepoint: Preintubation vitals,post intubation vitals at 1,2,3,5 minutes <br/ ><br>Time required for recovery from muscle relaxant after intubation dose
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