Clinical Trial to Evaluate intravenous esmolol hydrochloride infusion for postoperative analgesia in patients undergoing laparoscopic cholecystectomy
Not Applicable
Completed
- Registration Number
- CTRI/2010/091/001113
- Lead Sponsor
- nil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
age 18-65
Patient undergoing laparoscopic cholecystectomy
ASA I & II
Exclusion Criteria
1.Age <18 years or > 65 years
2.ASA > II
3.History of hepatic, renal, or cardiac failure
4.Morbid obesity ( BMI > 40 kg/m2)
5.Chronic use of opioid or β-adrenergic receptor blocker
6.Known case of asthma or reactive airway disease
7.Severe mental impairment
8.Allergy to local anaesthetics
9.Inability to comprehend pain assessment
10.Patients with poorly controlled diabetes mellitus
11.Patients with organ transplant
12.Conversion to open cholecystectomy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of intraoperative intravenous esmolol hydrochloride infusion v/s placebo infusion (Ringer?s Lactate) along with fentanyl citrate on postoperative analgesia requirement in patients undergoing laparoscopic cholecystectomy.Timepoint: Till 12 hours postoperative
- Secondary Outcome Measures
Name Time Method To study the incidence of side effects occurring in the two groups in the study designTimepoint: Till 12 hours postoperative