Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Pain
研究概览
简要总结
Numbers of postoperative PCA related side effects among three groups will be determined by comparing and analyzing frequency distributions. To determine whether the patients with hypertension require less post operative opiate analgesics than others, multivariate analysis with repeated measures will be performed to identify the major and the minor factors predicting the use of postoperative pain therapy. The major aim of the study is to test the hypothesis that the morphine comsumpted by the hypertension group is less than those of the normotension group. The minor aims for the study are the difference related to pain intensity, or the incidence of side effects among groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •300 eligible subjects
- •No contraindication for inhalation anesthesia
- •Elective surgery
- •Age between 20-75 y/o
- •No contraindication for postoperative morphine pain control
- •Female or male
- •Essential hypertension stage I and II (140<=SBP<=180; 90<=DBP<=110)
排除标准
- •Liver disease
- •Renal disease
- •Those who is presumed to go to ICU after surgery
- •The patients with dementia or conscious disturbance
- •Pregnancy or breast feeding
- •Secondary hypertension
- •events in recent 6 months myocardial infarction cardiac bypass surgery unstable angina cerebrovascular events congestive heart failure significant arrhythmia thoracic surgery
结局指标
主要结局
Pain
时间窗: Post-operation Day1 to Day4
次要结局
- Morphine consumption(Post-operation Day1 to Day4)
研究者
Yuan-Yi Chia
anesthesia doctor
Kaohsiung Veterans General Hospital.
