跳至主要内容
临床试验/NCT02244177
NCT02244177Unknown不适用

Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study

Kaohsiung Veterans General Hospital.1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2013年11月最近更新:
适应症

试验速览

阶段
不适用
入组人数
300
试验地点
1
主要终点
Pain

研究概览

简要总结

Numbers of postoperative PCA related side effects among three groups will be determined by comparing and analyzing frequency distributions. To determine whether the patients with hypertension require less post operative opiate analgesics than others, multivariate analysis with repeated measures will be performed to identify the major and the minor factors predicting the use of postoperative pain therapy. The major aim of the study is to test the hypothesis that the morphine comsumpted by the hypertension group is less than those of the normotension group. The minor aims for the study are the difference related to pain intensity, or the incidence of side effects among groups.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 300 eligible subjects
  • No contraindication for inhalation anesthesia
  • Elective surgery
  • Age between 20-75 y/o
  • No contraindication for postoperative morphine pain control
  • Female or male
  • Essential hypertension stage I and II (140<=SBP<=180; 90<=DBP<=110)

排除标准

  • Liver disease
  • Renal disease
  • Those who is presumed to go to ICU after surgery
  • The patients with dementia or conscious disturbance
  • Pregnancy or breast feeding
  • Secondary hypertension
  • events in recent 6 months myocardial infarction cardiac bypass surgery unstable angina cerebrovascular events congestive heart failure significant arrhythmia thoracic surgery

结局指标

主要结局

Pain

时间窗: Post-operation Day1 to Day4

次要结局

  • Morphine consumption(Post-operation Day1 to Day4)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yuan-Yi Chia

anesthesia doctor

Kaohsiung Veterans General Hospital.

研究点 (1)

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