Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers
- Conditions
- Hodgkin's LymphomaChronic Myeloid LeukaemiaNon-Hodgkin's LymphomaAcute Lymphoblastic LeukaemiaAcute Myeloid LeukaemiaMyelodysplastic SyndromeAcquired Bone Marrow Failure SyndromesOther Haematological Malignancies; Unrelated HSCT IndicatedChronic Lymphocytic Leukaemia
- Registration Number
- NCT01597219
- Lead Sponsor
- University College, London
- Brief Summary
This trial investigates stem cell transplants from partially mismatched donors in patients with blood and bone marrow cancers. The trial will test two kinds of transplants - a full intensity transplant using a high dose of radiotherapy and chemotherapy, and a reduced intensity transplant with lower doses of chemotherapy and radiotherapy. Patients will be entered for the treatment pathway that is most appropriate for their level of health and fitness
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 77
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Overall survival 1 year post transplant
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (12)
Birmingham Heartlands
🇬🇧Birmingham, United Kingdom
Bristol Royal Infirmary
🇬🇧Bristol, United Kingdom
Addenbrooke's Hospital
🇬🇧Cambridge, United Kingdom
Beatson Hospital
🇬🇧Glasgow, United Kingdom
St James' University Hospital
🇬🇧Leeds, United Kingdom
Royal Liverpool Hospital
🇬🇧Liverpool, United Kingdom
King's College Hospital
🇬🇧London, United Kingdom
St Bartholomew's Hospital
🇬🇧London, United Kingdom
University College Hospital
🇬🇧London, United Kingdom
Manchester Royal Infirmary
🇬🇧Manchester, United Kingdom
Scroll for more (2 remaining)Birmingham Heartlands🇬🇧Birmingham, United Kingdom