MedPath

Validation Study of the Accuracy of E/e' in Estimating Left Ventricular Filling Pressure

Not Applicable
Completed
Conditions
Doppler Echocardiography
Registration Number
NCT02883504
Lead Sponsor
Rennes University Hospital
Brief Summary

The non-invasive estimation of left ventricular end diastolic pressure (LVeDP) is a main goal for performing an echocardiography in the routine clinical practice. Conflicting evidence exists about mitral E/e' ratio reliability for predicting high LVeDP

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
85
Inclusion Criteria
  • Age over 18 years
  • Patient performing an echocardiography in the routine clinical practice
  • Informed consent given
Exclusion Criteria
  • Severe valve disease, valvular prostheses, calcification of the mitral valve, the history of myocardial infarction, atrial fibrillation, severe arrhythmias not allowing the Doppler analysis, pacemaker and any image by inadequate Doppler ultrasound
  • Major person under legal protection (backup justice, trusteeship, guardianship), person deprived of liberty.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Invasive evaluation of left ventricular end diastolic pressureD0

Left heart catheterization

Secondary Outcome Measures
NameTimeMethod
Non-invasive evaluation of left ventricular end diastolic pressureD0

Echo-Doppler

Trial Locations

Locations (1)

CHU Rennes

🇫🇷

Rennes, France

CHU Rennes
🇫🇷Rennes, France

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.