The Microcirculatory Profile in Necrotizing Enterocolitis

Completed

• Conditions: 10017943; 10028920; inflammatory condition of the bowel

• Registration Number: NL-OMON33444
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 180

Inclusion Criteria

Group 1:
- All neonates with sustained feeding intolerance and/or suspected NEC.
Group 2:
- Neonates without suspected NEC, matched for gender and gestational age with participants from group 1.
Group 3:
- All neonates with congenital gastrointestinal pathology.
For all groups: informed consent.

Exclusion Criteria

- Severe cardiac anomaly
- Severe respiratory anomalies
- Severe anomalies of the central nervous system

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is to determine the microcirculation and vascular<br /><br>reactivitiy in NEC.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are for example whether microcirculatory<br /><br>measurements can be used to predict which infants will need surgical<br /><br>intervention for NEC.</p><br>