Rhinosinusitis and nasal polyps in adults with Cystic Fibrosis

Completed

• Conditions: Cystic Fibrosis: mucoviscidosis; rhinosinusitis: paranasal sinus infection; sinusitis; 10038686; 10019815; 10046304

• Registration Number: NL-OMON36309
• Lead Sponsor: HagaZiekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

1. Confirmed diagnose of Cystic Fibrosis
2. Age * 18 years

Exclusion Criteria

1. Gross immunodeficiency (congenital of acquired)
2. Congenital mucociliary problems other than CF (e.g. Primairy ciliary dyskinesia)
3. ASA syndrome (Samter*s triad; nasal polyps, asthma, and aspirin sensitivity)
4. Cocaine abuse
5. Intranasal neoplasia
6. Systemic vasculitis and granulomatous diseases (e.g. M.Wegener, sarcoidosis, Churg-Strauss syndrome)
7. Pregnancy

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Prevalence of rhinosinusitis and/or nasal polyps. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Disease specific quality of life, outcome of ENT examination, nasal cultures,<br /><br>sputum culture, computed tomography of sinuses and nasal airway resistance.</p><br>