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Efficacy of Ketorolac with Lidocaine in Post Operative Pain Control in Wide Awake Open Carpal Tunnel Decompression Surgery, A Randomized Controlled Trial

Phase 3
Conditions
Carpal tunnel syndrome patients whose symptoms have not relieved with conservative treatment and requiring for a decompressive surgery
Ketorolac, Wide awake open carpal tunnel decompression surgery, carpal tunnel syndrome
Registration Number
TCTR20230908001
Lead Sponsor
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
42
Inclusion Criteria

1. Age between 18 - 65 years old
2. Patients with CTS confirmed by Orthopedics staff or resident
3. Desired for surgery
4. Willing to participate

Exclusion Criteria

1. End stage renal disease (ESRD) (GFR< 15 mL/min/1.73 m2)
2. Previous carpal tunnel decompression surgery in the same hand
3. Previous fracture at wrist
4. Rheumatoid arthritis, Cervical radiculopathy, cubital tunnel syndrome, thoracic outlet syndrome, cerebrovascular disease
5. Cognitive impairment
6. Acetaminophen or NSAIDs allergy
7. Unwilling to follow up

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Post-operative pain 1,2,4,24 hour post operation Visual analogue scale
Secondary Outcome Measures
NameTimeMethod
Hand function 1 2 week and 12 week post operation Carpal tunnel symptoms severity scale and functional status scale,Sleep disturbance score 1 day post operation Athens sleep scale,Total analgesic drug consumption 2 week post operation mg of drug consumption, time to first oral analgesic drug consumption,Hand function 2 2 week and 12 week post operation Composite fingr flexion distance (mm),Inflammatory score 2 week post operation serum ESR, CRP
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