Survey the effect of magnesium on coagulopathy of liver transplant patients.

Not Applicable

Completed

• Conditions: iver transplantation.; Surgical operation with transplant of whole organ

• Registration Number: IRCT2016012911662N9
• Lead Sponsor: Vice-Chancellery of Research and Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2018-02-22

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

The eligible participants were all patients with end stage liver disease aged between 18 and 60 years old, who were candidates for orthotopic liver transplantation under general anesthesia.
Exclusion criteria were: having a history of hepatorenal syndrome types ? and ??; baseline serum potassium >6 meq/l; ejection fraction <60% and cirrhotic cardiomyopathy and patients with INR <1.5.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of the coagulation profiles on rotational thromboelastometry (ROTEM) system. Timepoint: First time, before magnesium sulfate infusion and induction of anesthesia and second time, after magnesium sulfate infusion just before surgical incision. Method of measurement: By rotational thromboelastometry (ROTEM) system.

Secondary Outcome Measures

Name	Time	Method
Measurement of the serum magnesium level. Timepoint: First time, before magnesium sulfate infusion and induction of anesthesia and second time, after magnesium sulfate infusion just before surgical incision. Method of measurement: In the lab by special kit.