Comparing Pain Relief Methods After Gallbladder Surgery Using Local Injections

Phase 2/3

Not yet recruiting

• Conditions: Calculus of gallbladder and bile duct with cholecystitis,

• Registration Number: CTRI/2024/02/062680
• Lead Sponsor: DR RANJINI SHOME

Brief Summary

Laparoscopic cholecystectomy has gained popularity as day care procedure, still patients experience significant pain in early post operative period which may delay discharge. The aim of this study is to compare the analgesic efficacy of periportal and intraperitoneal infiltration of local anesthetic in patients undergoing lap cholecystectomy.

To compare the analgesic consumption in first 24 hours.

To comapre the incidence of adverse effects like shoulder tip pain and vomiting.

To compare the degree of early ambulation .

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-09-02
• Study Start: 2024-10-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1.ASA grades 1 and 2 of either sex.
• 2.Patients between age group of 20 to 60 years.
• 3.Undergoing elective laparoscopic cholecystectomy under General anesthesia.

Exclusion Criteria

• Patients with acute cholecystitis.
• Patients allergic to drug used in the study.
• Patients who have morbid obesity, choledocholithiasis, patients with chronic pain syndrome, previous upper abdominal surgery, chronic medical disease, chronic opiod treatment.
• Patients requiring placement of drain postoperatively.
• 5 Those with stone spillage.
• 6.Patients in whom conversion to open cholecystectomy was done for any reason.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
4.To compare degree of ambulation in postoperative period	8 weeks
1.To compare the analgesic efficacy of periportal and intraperitoneal infiltration of 0.25% Bupivacaine with Dexamethasone 4mg using visual analog scale.	8 weeks
2. to compare total analgesic consumption in first 24 hours.	8 weeks
3.To compare the incidence of adverse effects like shoulder pain , vomiting.	8 weeks

Secondary Outcome Measures

Name	Time	Method
to compare the incidence of adverse effects like shoulder tip pain, vomiting.	To compare the degree of ambulation.

Trial Locations

Locations (1)

Rajarajeswari medical college; 🇮🇳 Bangalore, KARNATAKA, India

Rajarajeswari medical college

🇮🇳Bangalore, KARNATAKA, India

DR Ranjini shome

Principal investigator

9108106959

ranjinishome8@gmail.com