Validation of Autoimmune Encephalitis severity scale in childre
Not Applicable
- Conditions
- Health Condition 1: G048- Other encephalitis, myelitis and encephalomyelitis
- Registration Number
- CTRI/2022/02/040510
- Lead Sponsor
- Prof Naveen Sankhyan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Fulfilling the clinical diagnostic criteria of autoimmune encephalitis (Cellucci et al 2020)
2. No preexisting neurological disorder like epilepsy, cerebral palsy, neurometabolic disorder, movement disorder or degenerative brain disease
Exclusion Criteria
1. No parental consent
2. Alternative disease diagnosed on follow up
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Validity (sensitivity, specificity)of PASS will be assessed by comparison with mRS and PedsQL score as per COnsensus-based Standards for the selection of health status Measurement INstruments(COSMIN) checklistTimepoint: 8 timepoints (Day7, day14, day 28 and then monthly till 6 months of presentation)
- Secondary Outcome Measures
Name Time Method Correlation of PASS will be assessed with CASE score and cognitive outcomeTimepoint: 6 months of presentation;Inter-rater agreement will be assessed using Kappa statisticTimepoint: NA;Internal consistency will be assessed by item-total correlation and Cronbach alphaTimepoint: NA;latent structure of these items using Restricted and non-restricted factor analytic modelsTimepoint: At the end of study