A study to assess the effect of dexmedetomidine and its safety in children undergoing surgery for undescended testes under general anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: N509- Disorder of male genital organs, unspecified
- Registration Number
- CTRI/2020/05/025315
- Lead Sponsor
- Indira Gandhi Institute of Child Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients belonging to ASA Grade I and Grade II.
Exclusion Criteria
1)Syndromic children with undescended testes.
2)Patients suffering from cardiac and pulmonary disease.
3)Severe obstructive sleep apnea.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of intravenous dexmedetomidine on intraoperative hemodynamic stability and its role in postoperative analgesia following laparoscopic Stephen- Fowlerâ??s stage-2 orchidopexy under general anaesthesia in pediatric patients. <br/ ><br>Timepoint: Heart rate, systolic blood pressure, oxygen saturation, end-tidal CO2, temperature will be recorded every 5 minutes intraoperatively, and postoperatively for 15 minutes followed by every 30 min for 1 hour. Extubation quality will be graded at extubation. Agitation scores observed every 15 minutes for 1 hour. Pain score every 2 hours for 6 hours followed by every 4 hours for 24 hours. Time for first dose of rescue analgesic and time to discharge will be documented. <br/ ><br>
- Secondary Outcome Measures
Name Time Method To study the effect of dexmedetomidine on airway reflexes and hemodynamic responses during tracheal extubation. <br/ ><br>Timepoint: Extubation
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of Dexmedetomidine in modulating haemodynamics during pediatric laparoscopic surgery for undescended testes?
How does intravenous Dexmedetomidine compare to regional anaesthesia in terms of postoperative analgesic requirements and recovery profiles in children undergoing laparoscopic Stephen-Fowlers stage-2 repair?
Are there specific biomarkers that can predict patient response to Dexmedetomidine in the context of general anaesthesia for undescended testes surgery?
What are the potential adverse events associated with Dexmedetomidine use in pediatric patients and how can they be managed effectively?
What are the current drug classes and combination approaches used in managing intraoperative haemodynamics and postoperative analgesia in pediatric urological surgeries?