Comparison Efficacy of Intraarticular Knee Injection in Knee Osteoarthritis With Leukocyte-rich and Leukocyte-poor Platelet-rich Plasma

Phase 2

Completed

• Conditions: Osteoarthritis of the knee; Osteo Arthritis Knee

• Registration Number: TCTR20230217004
• Lead Sponsor: Queen Savang Vadhana Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-11-03
• Study Start: 2023-02-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

Age greater than or equal to 50 years old,
Plain radiographs knee AP shows Kellgren-Lawrence classification 1-4,
Refuse the use of NSAIDs for 2 weeks.

Exclusion Criteria

1) Previous intra-articular injection therapy in the past 6 months;
2) Previously treated with intra-knee PRP injection;
3) History of knee arthritis from other causes such as rheumatoid arthritis, pseudogout or infectious joints
4) History of blood disorder including anemia and thrombocytopenia (Hb < 12 g/dl, plt < 150,000/ml )
5) History of surgery on the aforementioned knee
6) Obvious knee deformity (valgus > 15, varus > 20, flexion ROM < 90, extension lag > 20)
7) Pregnancy and lactation

Study & Design

• Study Type: Interventional
• Study Design: Not specified