Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer
- Conditions
- Lung Cancer
- Registration Number
- NCT00213733
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).
- Detailed Description
Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
- Informed consent is required.
- Another cancer
- Chemotherapy before surgical treatment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (5)
Service de Chirurgie Thoracique, Hôpital Civil
🇫🇷Strasbourg, France
Service de Pneumologie, Hôpital Lyautey
🇫🇷Strasbourg, France
Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre
🇫🇷Strasbourg, France
Service d'Anatomie Pathologique, Hôpital de Hautepierre
🇫🇷Strasbourg, France
Service de Pneumologie, Hôpital de Hautepierre
🇫🇷Strasbourg, France
Service de Chirurgie Thoracique, Hôpital Civil🇫🇷Strasbourg, France