Research of Molecular Markers for Diagnosis and/or Prognosis in Lymph Node Metastasis of Resected Non-small Cell Lung Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lung Cancer
- Sponsor
- University Hospital, Strasbourg, France
- Enrollment
- 150
- Locations
- 5
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).
Detailed Description
Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
- •Informed consent is required.
Exclusion Criteria
- •Another cancer
- •Chemotherapy before surgical treatment
Outcomes
Primary Outcomes
Not specified