Comparative evaluation of antimicrobial efficacy and Inter-appointment pain with 3% sodium hypochlorite at different intracanal temperatures in teeth with Pulp necrosis with Symptomatic Apical periodontitis- A Randomized Clinical Study

Sodium hypochlorite (NaOCl) is the most common irrigant used in endodontics because of its antibacterial and physicochemical properties and its unique ability to dissolve necrotic tissue remnants. Mechanical instrumentation and NaOCl irrigation have been shown to dramatically reduce the bacterial load in the root canal system. Unfortunately, irrigation with NaOCl during chemo-mechanical debridement does not always result in bacteria-free root canals. In teeth with symptomatic apical periodontitis, patients undergoing cryotherapy treatment exhibited a significant reduction in inter-appointment pain levels compared to the control group.5 So far, the effect of different concentrations or temperatures of sodium hypochlorite on pain after endodontic treatment has been investigated. Consequently, there are no clinical studies to support the use of preheated NaOCl for root canal irrigation. Therefore, the research question of this study is to evaluate whether the effect of 3% sodium hypochlorite at different intracanal temperatures would result in a difference in antimicrobial efficacy and inter-appointment pain in teeth with Pulp necrosis with symptomatic apical periodontitis treated in two visits. The result of this study will help us to know about the antibacterial efficacy of cryotherapy with sodium hypochlorite as a root canal irrigant