ISRCTN22305120已完成不适用
The role of platelet activation and inflammation in the adverse Cardiovascular outcomes of patients undergoing surgery for Critical Limb ISchaemia: a double-blind randomised controlled trial of clopidogrel
othian Health Board (LHB) (UK)0 个研究点目标入组 100 人开始时间: 2008年6月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients aged greater than 45 years, either sex
- •2. Critical limb ischaemia, defined as the presence of rest pain or skin breakdown, and an ankle-brachial pressure index less than 0.2
- •3. Scheduled for infra-inguinal bypass, endarterectomy or amputation under general anaesthesia
排除标准
- •1. Women of child bearing potential
- •2. Non-atherosclerotic vascular disease
- •3. Sudden acute limb ischaemia requiring emergency surgery
- •4. Supra-inguinal or aortic surgery
- •5. History of acute coronary syndrome within three months
- •6. History of peptic ulcer disease
- •7. Previous or current intracranial haemorrhage
- •8. Bleeding diathesis
- •9. Uncontrolled hypertension or thrombocytopenia
- •10. Planned epidural or spinal anaesthesia
- •11. Hypersensitivity or allergy to thienopyridines
- •12. Current warfarin or thienopyridine use
研究者
相似试验
进行中（未招募）
1 期
Role of Inflammation and Platelet Activation in the adverse Cardiovascular Outcomes of Patients with Critical Limb Ischaemia - a double-blind randomised trial of Clopidogrel. - Platelet activation and Clopidogrel in Critical Limb IschaemiaPeripheral Vascular Disease (Critical Limb Ischaemia)EUCTR2005-000960-25-GBothian NHS trust200
已完成
不适用
The role of inflammatory mediators (platelet activity,the number and origin of micro particles and levels of mitochondrial DNA) in patient with acute renal transplant rejection.acute renal transplant injuryrenal inflammation1000381610029149NL-OMON41402Academisch Medisch Centrum65
已完成
不适用
Platelet activation and responsiveness in patients with acute exacerbations of chronic obstructive pulmonary disease (AE-COPD)NL-OMON45449Academisch Medisch Centrum30
已完成
不适用
Platelet reactivity, inflammation and endothelial dysfunction during and after exacerbation in chronic obstructive pulmonary disease (COPD) patientsChronic Obstructive Pulmonary DiseaseNL-OMON46302Gelre Ziekenhuizen76
已完成
不适用
Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.Septic ShockNCT04080453University Hospital, Bordeaux202