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临床试验/NCT03954353
NCT03954353已完成不适用

Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries

Peking University First Hospital1 个研究点 分布在 1 个国家目标入组 78,888 人开始时间: 2019年5月17日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
78,888
试验地点
1
主要终点
post-operative acute kidney injury within 30 days in the hospital

研究概览

简要总结

Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown. This study aimed to explore the effect in non-cardiac surgical population.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adults elective non-cardiac surgery

排除标准

  • cardiac surgeries kidney surgeries obstetric surgeries local infiltration anesthesia perioperative data missing

结局指标

主要结局

post-operative acute kidney injury within 30 days in the hospital

时间窗: 30 days postoperatively in hospital

It was defined by patient's postoperative serum creatine increase no less than 26.5 μmol/l within 48 hours, or 1.5 times from baseline within the 7 days after surgery or initializing blood dialysis.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yan Zhou, MD

Principal Investigator

Peking University First Hospital

研究点 (1)

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