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Comparisons of changes in circulating vascular endothelial growth factor-A and renal vascular parameters after intravitreal ranibizumab or aflibercept for retinal vascular disease

Not Applicable
Conditions
age-related macular degeneration, diabetic macular edema, macular edema secondary to retinal vein occlusion
Registration Number
JPRN-UMIN000036143
Lead Sponsor
Tosei General Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients who had received systemic anti-VEGF therapy for malignancy. 2)Patients who were currently on dialysis. 3)Patients who had undergone vitrectomy in the treated eye. 4)Patients who had severely high albuminuria (A3 category, KDIGO 2012).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
rine albumin to creatinine ratio 3 months after treatment
Secondary Outcome Measures
NameTimeMethod
1)Circulating total VEGF-A and VEGF-A165b levels 3 months after treatment 2)Blood pressure 3 months after treatment 3)Ankle brachial index 3 months after treatment
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