Inflammation in femoral fractures

Not Applicable

• Conditions: Fracture of shaft of femur.; Fracture of shaft of femur

• Registration Number: IRCT2014110519818N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Our findings suggest that serum levels of IL-8 were markedly decreased from 12 h until 48 h postoperatively (p < 0.05). Moreover, the results indicated that serum levels of TNF-? were significantly increased in the early hours, but after 48 h a decreasing trend was detected (p < 0.05). Furthermore, serum levels of IL-10, IFN-?, and IL-6 were significantly increased from 12 h until 48 h postoperatively (p < 0.05)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

Fracture of femoral shaft
no any other concomitant injury
aging from 20 to 50 years

Exclusion Criteria

Presence of concomitant injuries
presence of chronic inflammatory diseases

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Interferon Gamma. Timepoint: one hour after surgery. Method of measurement: Lab Kit.;Interleukin 1. Timepoint: one hour after surgery. Method of measurement: Lab Kit.;Interleukin 5. Timepoint: one hour after surgery. Method of measurement: Lab Kit.;Interleukin 6. Timepoint: one hour after surgery. Method of measurement: Lab Kit.;TNF-Alph. Timepoint: one hour after surgery. Method of measurement: Lab Kit.

Secondary Outcome Measures

Name	Time	Method
Interlukin 1. Timepoint: One hour after surgery. Method of measurement: Lab Kit.;IFN-Gamma. Timepoint: One hour after surgery. Method of measurement: lab kit.;TNF-Alpha. Timepoint: one hour after surgery. Method of measurement: lab kit.;Interlukin 5. Timepoint: one hour after surgery. Method of measurement: lab kit.;Interlukin 6. Timepoint: one hour after surgery. Method of measurement: lab kit.