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Effects of Monascus Garlic Fermented Extract on Serum Triglyceride Level

Not Applicable
Completed
Conditions
Hypertriglyceridemias
Interventions
Dietary Supplement: Monascus Garlic Fermented Extract
Dietary Supplement: Placebo
Registration Number
NCT00938249
Lead Sponsor
Hiroshima University
Brief Summary

The purpose of the study is to determine the effect of monascus garlic fermented extract on serum lipid concentrations in subjects with moderately elevated serum triglyceride.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
55
Inclusion Criteria
  • Healthy as based on medical history and physical examination
  • Fasting serum triglyceride 120 to 200mg/dl
  • Willing not to serve as blood donor during the study
  • Informed consent signed
Exclusion Criteria
  • Female subjects who are pregnant or nursing a child
  • Participation in any clinical trial up to 90 days before Day 1 of this study
  • Renal or hepatic dysfunction
  • Heart disease
  • Under medication
  • Subjects who are taking functional food designed for weight loss or serum lipid reduction

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Monascus Garlic Fermented ExtractMonascus Garlic Fermented Extract-
PlaceboPlacebo-
Primary Outcome Measures
NameTimeMethod
Fasting triglyceride levelEvery 4 weeks (Overall 20 weeks)
Secondary Outcome Measures
NameTimeMethod
Abdominal circumferenceEvery 4 weeks (Overall 20 weeks)
Visceral fat area by CT scanWeek 0 and Week 12
Serum total cholesterol and LDL cholesterol levelsEvery 4 weeks (Overall 20 weeks)
Serum adiponectin levelWeek 0 and Week 12

Trial Locations

Locations (1)

Hiroshima University

🇯🇵

Hiroshima, Japan

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