Effect of aged garlic extract on cardiovascular health: a randomized 12-week placebo-controlled study
Phase 2
Recruiting
- Conditions
- HypertensionC14.907.489
- Registration Number
- RBR-69c4qq
- Lead Sponsor
- niversidade Federal de Sergipe
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Arterial hypertension
Exclusion Criteria
Psychiatric disorder; allergy to garlic and sulfur; terminal illness; anemia; infection; pregnancy; use of multivitamin or garlic supplement in the last 6 months; can not give informed consent; are participating in another clinical trialand and malnutrition
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expected outcome 1: blood pressure control, ie, reduction of blood pressure in patients who received the garlic extract aged in relation to those who will receive the placebo.;Expected outcome 2: the hypotensive effect of the aged garlic extract will occur in patients with adequate nutritional status of vitamins B6, B9 and B12.
- Secondary Outcome Measures
Name Time Method Reduction of cardiovascular markers: blood lipids, such as HDL-c, LDL-c, and total cholesterol<br><br>Reduced fasting blood glucose.<br><br>Reduction of anthropometric measures: Percentage of fat and waist circumference