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Use of Testicular Spermatozoa in Non-azoospermic Patients

Conditions
Male Infertility
Interventions
Procedure: Testicular sperm extraction (TESE)
Registration Number
NCT05203211
Lead Sponsor
Istituto Clinico Humanitas
Brief Summary

Use of testicular spermatozoa in non-azoospermic patients.

Detailed Description

The aim of the study is to evaluate the characteristics of couples whose male partner is offered TESE after the failure of previous ICSI technique performed with ejaculated semen. All couples in a third-level University affiliated centre, between January 2010 and January 2020, whose male partner were diagnosed with any type of oligospermia and underwent TESE after ICSI from ejaculated semen, were included in the analysis.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Male
Target Recruitment
120
Inclusion Criteria
  • All patients undergone testiscular sperm extraction (TESE) after failure of ICSI with the use of ejaculated sperm
Exclusion Criteria
  • Female age >40 yo

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Men who have undergone icsi from testicular spermTesticular sperm extraction (TESE)-
Primary Outcome Measures
NameTimeMethod
fertilization rate (FR)10 years

Evaluate if there is a higher fertilization rate in male patients undergone TESE

Secondary Outcome Measures
NameTimeMethod
Blastulation rate (BR)10 years

Evaluate if there is a higher blastulation rate in male patients undergone TESE

Miscarriage rate (MR)10 years

Evaluate if there is a lower miscarriage rate in male patients undergone TESE

Trial Locations

Locations (1)

Istituto Clinico Humanitas

🇮🇹

Rozzano, Milano, Italy

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