Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia
- Conditions
- Azoospermia
- Interventions
- Procedure: Bone marrow stem cell injection
- Registration Number
- NCT02008799
- Lead Sponsor
- Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
- Brief Summary
Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being "sterile" or having "testicular failure." We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 20
- Azoospermia
- Absent or surgical removed testes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Bone marrow stem cell injection Bone marrow stem cell injection through special butterfly inject stem cell in testicular artery and inside tubules
- Primary Outcome Measures
Name Time Method Semen Analysis Three to six months After stem cell injection by three to six months we evaluate the outcome by semen analysis
- Secondary Outcome Measures
Name Time Method Inhibin B Hormone Three to six months If semen analysis still azoo we do Inhibin B Hormone
Trial Locations
- Locations (1)
Man Clinic
🇪🇬Cairo, Egypt