An in situ model to study erosive enamel tooth wear, a clinical pilot study

Completed

• Conditions: gebitsaandoening, nl. erosieve gebitsslijtage; dental erosion; erosive tooth wear

• Registration Number: NL-OMON40477
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 6

Inclusion Criteria

- The volunteers need to wear a full denture in upper jaw and lower jaw.
- 40-65 years of age
- unstimulated and stimulated saliva flow rate of > 0,25 and >0,75 ml/min, respectively

Exclusion Criteria

- Use of medication which can influence salivary flow.
- Self reported or observed grinding or clenching habit
- Symptoms of gastro-oesophageal reflux (heartburn, regurgitation, vomiting)
- Vegetarian diet
- Abnormal drinking habits (e.g. swishing or holding of drinks before swallowing).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>After averaging the surface loss calculations per tooth site (sample area),<br /><br>mean tissue loss and mean standard deviation for each tooth site and total<br /><br>tissue loss per person are calculated over each study period. The primary<br /><br>analysis estimates the erosive effect of the consumption of orange juice on the<br /><br>outcome variable the profilometrically measured tissue loss, expressed in<br /><br>micrometers. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary analysis will evaluate surface loss distribution by tooth site<br /><br>(occlusal, palatal, buccal, and upper / lower jaw, left/right quadrant).</p><br>