Tolerance induction through early feeding to prevent food allergy in infants with eczema

Not Applicable

Recruiting

• Conditions: T78.1; L20.9; Other adverse food reactions, not elsewhere classified; Atopic dermatitis, unspecified

• Registration Number: DRKS00016770
• Lead Sponsor: Charité Campus Charité Mitte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1. children, age 4-8 months
2. eczema
3. signed informed consent of parents

Exclusion Criteria

- previous consumption of hen´s egg, peanut or hazelnut
- wheat allergy
- severe diseases (cardiac, congenital)
- participation in another interventional Trial

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Food allergy to at least on one of the following Foods: hen´s egg, cow´s milk, hazelnut and peanut at around one year of age.

Secondary Outcome Measures

Name	Time	Method
1. Allergic reactions during Intervention<br>2. Multiple food allergies, bronchial asthma, changes in disease severity of eczema<br>3. Changes of the microbiome (Skin and gut), changes in immunological processes<br>4. Identification of genetic and epigenetic factors associated with Food allergy <br>5. Identification of biomarker characterizing anaphylactic reactions