Perceptual correlate of nociceptive long-term potentation (LTP) in the greater occipital nerve (GON) and the three branches of the trigeminal nerve after electrical high frequency stimulation (HFS) of the first trigeminal branch, V1, and the GON, respectively.
Not Applicable
Recruiting
- Conditions
- Trigeminocervical complex in healthy participants
- Registration Number
- DRKS00012442
- Lead Sponsor
- niversitätsklinikum Hamburg-Eppendorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Healthy subjets, that do not fulfill any exclusion critera.
Exclusion Criteria
Pain and/or headache disorders (people reporting infrequent episodic TTH are accepted as long as they have less than 12 episodes a year), 1. Generation family member with primary headache disorder, skin lesions or other dermatological disorders in the applied areas (neck and face region), men with full beard, neurological, psychiatric or other chronic disorders, whiplash or other damages to the cervical spine, pregnancy or breast feeding, misuse of alcohol or drugs, inability to speak or understand German
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perceptive pain ratings of each of the electrical stimulations, single pulses as well as high frequency stimulations. <br>The stimulations are rated on a visual analog scale (VAS) corresponding 0 (no pain) through to 100 (worst imaginable pain) and are registered by the subject on a computer immediately after each stimulation.
- Secondary Outcome Measures
Name Time Method