The effect of zinc supplementation on semen parameters, serum and seminal zinc levels of oligozoospermic men attending University of Ilorin Teaching Hospital (UITH): A randomized double - blind trial.
- Conditions
- Fertility-male
- Registration Number
- PACTR202304634296590
- Lead Sponsor
- Sadiya Musa Gwadabe
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 82
1. Male partners of infertile couple within the age of 20-59years having regular unprotected intercourse for a year or more.
2. Men with sperm concentration <15million cells/ml on two occasions 4 weeks apart.
3. Male partners with normal descended testes.
4. Patient who consent to participate in the study
1. Men with the following problems will be exckuded:Aspermia, azoospermia, testicular varicocele, ongoing sexually transmitted disease, chronic illness, serious systemic disease like diabetes, endocrine and metabolic disorders, smoking, alcohol intake and previous groin or scrotal surgery
2. Men that have used zinc within three months of recruitment /other supplements
3. Men on drugs that suppress spermatogenesis such as steroidsand other immunosuppressive drugs
4. Men with immunosuppressive disease like Human Immunodeficiency Virus (HIV) and malignancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Baseline seminal and serum zinc levels 2. Serum and seminal zinc level after administration of zinc sulphate or placebo. 3. Baseline sperm count 4. Sperm count after administration of zinc sulphate or placebo
- Secondary Outcome Measures
Name Time Method 1. Semen parameters (Concentration, motility, morphology and volume) after administration of zinc sulphate and placebo. 2. Adverse effects of the Intervention drug reported by the patients.