Midazolam's Anterograde Amnesia Efficacy in Noisy Orthopedic Surgery: Does Midazolam Cause Effective Anterograde Amnesia in Noisy Orthopedic Surgeries?
Overview
- Phase
- Not Applicable
- Intervention
- spinal anesthesia with no sedation.
- Conditions
- Anesthesia
- Sponsor
- University of Jordan
- Enrollment
- 116
- Locations
- 1
- Primary Endpoint
- Postoperative recall of auditory stimuli and intraoperative noise
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia. The aim of this study is to investigate visual, recall, auditory recall, and sedation scores among patients receiving Midazolam for sedation during spinal anesthesia in patients undergoing orthopedic surgeries.
Detailed Description
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia. The main goals of sedation for surgeries under spinal anesthesia are patient comfort, preservation of protective airway reflexes, and the help in the maintenance of hemodynamic stability during the surgical procedure. The aim of this study is to investigate visual, recall, auditory recall, and sedation scores among patients receiving Midazolam for sedation during spinal anesthesia in patients undergoing orthopedic surgeries.
Investigators
Mahmoud M. Almustafa
Principal Investigator
University of Jordan
Eligibility Criteria
Inclusion Criteria
- •patients undergoing total knee or total hip replacement.
- •ASA I, II, or III.
- •patients undergoing spinal anesthesia.
Exclusion Criteria
- •patient refusal.
- •\<24 hours sedative administration.
- •patient with hearing impairment.
- •neurological or memory disorder.
- •abnormal kidney function tests.
- •any contraindication for spinal anesthesia.
Arms & Interventions
Group C (control group)
control group will receive no sedation under spinal anesthesia.
Intervention: spinal anesthesia with no sedation.
Group O (single dose group)
patients will receive 0.025mg/kg midazolam sedation under spinal anesthesia.
Intervention: single-dose midazolam for sedation under spinal anesthesia.
Group M (double dose group)
patients will receive 0.025mg/kg midazolam sedation twice under spinal anesthesia.
Intervention: Double-dose midazolam for sedation under spinal anesthesia.
Outcomes
Primary Outcomes
Postoperative recall of auditory stimuli and intraoperative noise
Time Frame: 4 months
For auditory recall, a question was asked by the surgeon to the patient at maximum stimulation. Patients were examined for auditory recall by following-up the patients postoperatively in the inpatient department.
Postoperative recall of visual stimuli
Time Frame: 4 months
For visual recall, a picture of a horse assigned at maximum stimulation, a cat at recovery room, and a bird after discharge to the inpatient department. Patients were examined for visual recall by following-up the patients postoperatively in the inpatient department.